Single-center thorough evaluation and targeted treatment of globozoospermic men
نویسندگان
چکیده
منابع مشابه
I-2: Current Evaluation and Treatment of The Infertile Men
Background Fifty percent of infertility involves a male factor. The evaluation begins with a history, physical exam and semen analysis x 2. The history should include questions about exposure to gonad toxins. The differential diagnosis of no ejaculate includes; retrograde ejaculation, failure of ejaculation (rare), failure of emission and psychogenic. Evaluation of absence of the vas deferens w...
متن کاملProduction and Evaluation of Specific Single-Chain Antibodies against CTLA-4 for Cancer-Targeted Therapy
Background: Cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) molecules are expressed on T-cells and inhibit their function by inhibiting activation of subsequent T-cell molecular pathways. Blocking of CTLA-4 inhibits the growth of malignant tumor cells. Anti-CTLA-4 monoclonal antibodies activate the immune system against cancer. Due to several advantages of single-chain antibodi...
متن کاملEvaluation of PLCζ and PAWP Expression in Globozoospermic Individuals
OBJECTIVE Globozoospermia is a rare type of teratozoospermia with incidence of 0.1% among infertile individuals. Phospholipase C zeta (PLCζ) and postacrosomal sheath WW domain binding protein (PAWP) are the main candidates in sperm taking responsibility for oocyte activation during fertilization. Therefore, we aimed to evaluate the expression of these two genes at RNA and protein levels in glob...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2021
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-021-02191-4